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Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction; 1 [Score: 100%]
Author / Editor: Sperka, Tobias; Rudolph, Karl Lenhard |  Place of publication: London |  Publisher: Nature Publishing Group |  Year of Publication: 2012 | 7 s.
Journal / Series / Collection: Nature cell biology; 14
Subject Area: Medizin; Biologie
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Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation; 1 [Score: 100%]
Author / Editor: Choudhury, Aaheli Roy; Rudolph, Karl Lenhard |  Place of publication: New York, NY |  Publisher: Nature Publishing Group |  Year of Publication: 2007 | 7 s.
Journal / Series / Collection: Nature genetics; 39
Subject Area: Biologie; Medizin
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p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice; 10 [Score: 100%]
Author / Editor: Begus-Nahrmann, Yvonne; Rudolph, Karl Lenhard |  Place of publication: New York, NY |  Publisher: Nature Publishing Group |  Year of Publication: 2009 | 6 s.
Journal / Series / Collection: Nature genetics; 41
Subject Area: Biologie; Medizin
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Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment; 6 [Score: 100%]
Author / Editor: Ju, Zhenyu; Rudolph, Karl Lenhard |  Place of publication: New York, NY |  Publisher: Nature Publishing Group |  Year of Publication: 2007 | 6 s.
Journal / Series / Collection: Nature medicine; 13
Subject Area: Medizin
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DNA damage checkpoints in stem cells, ageing and cancer; 9 [Score: 100%]
Author / Editor: Sperka, Tobias; Wang, Jianwei; Rudolph, Karl Lenhard |  Place of publication: London |  Publisher: Nature Publishing Group |  Year of Publication: 2012 | 12 s.
Journal / Series / Collection: Nature reviews molecular cell biology; 13
Subject Area: Biologie; Medizin
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