8 hits in 0.009 sec.
Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane
[Score: 100%]
Author / Editor: Kaether, Christoph; Haass, Christian | Place of publication: New York, NY | Publisher: Rockefeller University Press | Year of Publication: 2002 | 11 s.
Journal / Series / Collection: The journal of cell biology; 158
Subject Area: Biologie; Chemie und Pharmazie; Medizin
Author / Editor: Kaether, Christoph; Haass, Christian | Place of publication: New York, NY | Publisher: Rockefeller University Press | Year of Publication: 2002 | 11 s.
Journal / Series / Collection: The journal of cell biology; 158
Subject Area: Biologie; Chemie und Pharmazie; Medizin
Amyloid beta-peptide is produced by cultured cells during normal metabolism; 6393
[Score: 100%]
Author / Editor: Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 1992 | 4 s.
Journal / Series / Collection: Nature; 359
Subject Area: Chemie und Pharmazie; Biologie
Author / Editor: Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 1992 | 4 s.
Journal / Series / Collection: Nature; 359
Subject Area: Chemie und Pharmazie; Biologie
Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases; 11
[Score: 100%]
Author / Editor: Steiner, Harald; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2000 | 4 s.
Journal / Series / Collection: Nature cell biology; 2
Subject Area: Biologie
Author / Editor: Steiner, Harald; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2000 | 4 s.
Journal / Series / Collection: Nature cell biology; 2
Subject Area: Biologie
Reconstitution of gamma-secretase activity; 5
[Score: 100%]
Author / Editor: Edbauer, Dieter; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2003 | 3 s.
Journal / Series / Collection: Nature cell biology; 5
Subject Area: Biologie
Author / Editor: Edbauer, Dieter; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2003 | 3 s.
Journal / Series / Collection: Nature cell biology; 5
Subject Area: Biologie
Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch; 4
[Score: 100%]
Author / Editor: Capell, Anja; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2000 | 7 s.
Journal / Series / Collection: Nature cell biology; 2
Subject Area: Biologie
Author / Editor: Capell, Anja; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2000 | 7 s.
Journal / Series / Collection: Nature cell biology; 2
Subject Area: Biologie
The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity; 24
[Score: 100%]
Author / Editor: Kaether, Christoph; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2004 | 11 s.
Journal / Series / Collection: The EMBO journal; 23
Subject Area: Biologie; Chemie und Pharmazie
Author / Editor: Kaether, Christoph; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2004 | 11 s.
Journal / Series / Collection: The EMBO journal; 23
Subject Area: Biologie; Chemie und Pharmazie
Presenilins mediate a dual intramembranous gamma-secretase cleavag of Notch-1; 20
[Score: 100%]
Author / Editor: Okochi, Masayasu; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2002 | 9 s.
Journal / Series / Collection: The EMBO journal; 21
Subject Area: Biologie; Chemie und Pharmazie
Author / Editor: Okochi, Masayasu; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2002 | 9 s.
Journal / Series / Collection: The EMBO journal; 21
Subject Area: Biologie; Chemie und Pharmazie
A gamma-secretase-like intramembrane cleavage of TNFAlpha by the GxGD aspartyl protease SPPL2b; 8
[Score: 100%]
Author / Editor: Fluhrer, Regina; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2006 | 3 s.
Journal / Series / Collection: Nature cell biology; 8
Subject Area: Biologie
Author / Editor: Fluhrer, Regina; Haass, Christian | Place of publication: London | Publisher: Nature Publishing Group | Year of Publication: 2006 | 3 s.
Journal / Series / Collection: Nature cell biology; 8
Subject Area: Biologie